The knowledgeable Los Angeles history aficionados at the Vintage Los Angeles page on Facebook located this scene as the 1950s at Santa Monica Boulevard and Fairfax, known then as the Crescent Junction on the Pacific Electric rail network. (Note the store is Crescent Drugs.) The car is about to turn right and head west on Santa Monica. The camera is looking to the northeast, where the tracks will connect with Sunset Boulevard. The corner is now occupied by a Whole Foods market.
The photo was posted by Jerome Melgar.